反復性多発性軟骨炎（relapsing polychondritis）の2症例と本邦眼科領域報告症例の総括

Two cases of relapsing polychondritis with ocular complications

　反復性多発性軟骨炎と思われる2例につき眼症候を中心に報告した．また，本邦眼科領域で過去に報告された4症例の眼症候をまとめた．眼症候としては虹彩毛様体炎・強膜炎（上強膜炎）・角膜混濁が多くみられる．これらの症候は長期にわたり増悪・緩解をくり返す特微がみられる．治療は副腎皮質ステロイドが有効である．本疾患に合併した眼病変の予後は比較的良好である．

Two cases of relapsing polychondritis associated with ocular complications are reported. One case, a 61-year-old woman, had a ten-year history of bilateral, recurrent episcleritis and iritis of several days duration. For the recent years she had also suffered from cartilaginous inflammations of the earlobes, larynges and ribs recurring several times a year. The other case, a 41-year-old man, had bilateral, recurrent episcleritis, iritis and optic neuritis preceded or following by episodic car-tilaginous inflammations of the earlobes and hands.The clinical features of these cases were consistent with those of relapsing polychondritis, and labo-ratory examinations of the blood revealed various immunological abnormalities. The incidence of this disease is yet to be elucidated, and four cases have previously been documented in the Japanese ophthalmic literature. A brief review was made on the ocular involvements of relapsing polychon-dritis.