Chandler症候群の2例

Two cases of Chandler's syndrome

　1）48歳男性と50歳男性のChandler症候群2例を報告した。

　2）症例の特徴は他覚所見として，角膜内皮変性と角膜浮腫，軽度の虹彩萎縮，強い周辺虹彩前癒着，軽度の眼圧上昇などがあり，自覚症状として視力障害を訴え，いずれも片眼性で，家族発生をみていないことである。

　3）治療は主に角膜液腫に向けられ，降圧剤の点眼・内服，高張液の点眼などの対症療法を行ない，現在，良好な経過をとっている。

Two adult males, 48 and 50 years of age, mani-fested clinical features of Chandler's syndrome. Only the left eye was involved in either case. These cases were characterized by slight atrophy of the iris, peripheral anterior synechias, moderate eleva-tion of intraocular pressure and corneal edema. Peculiarly, specular microscopy revealed the endo-thelial cells to be enlarged in size in both instances. The family history was inconspicuous.

The therapeutic efforts were mainly directed to alleviate the corneal edema by means of miotics, hyperosmotic agents, and acetazolamide among others.