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THE REMOTE EFFECTS OF BRAIN TUMORS ON CEREBRAL BLOOD FLOW AS MEASURED BY SINGLE PHOTON EMISSION CT Yuzo Araki 1 , Yukinori Imao 1 , Noboru Sakai 1 , Kotoyuki Shimizu 1 , Toshihumi Hirata 1 , Hiromu Yamada 1 1Department of Neurosurgery, University of Gifu School of Medicine pp.367-374
Published Date 1989/4/1
DOI https://doi.org/10.11477/mf.1406206294

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  • Abstract
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In order to assess the remote effects of supra-tentorial brain tumors, the cerebellar blood flow and cerebral blood flow of the symmetrical re-gions in the contralateral cerebral hemispspheres were measured by single photon emission CT. Forty four patients with supratentorial brain tu-mors, such as gliomas, meningiomas and germ cell tumors etc., were included in this study.

Contralateral cerebellar hypoperfusion (CCH) was exihibited in 51%, 18 of 35 unilateral brain tumors. Regarding tumor location, CCH was more correlated with frontoparietal lesions.

The mean values of contralateral ΔCerebellar blood flows (ΔCBFs) were lower than those of ipsilateral ΔCeBFs, and also statistically, bilateral tICeBFs significantly decreased. The greater the volume of lesions including peritumoral edemas,the lower the ΔCeBF became. Among the 9 cases with obstructive hydrocephalus, the preoperative ΔCeBFs which had decreased significantly, return-ed to normal postoperatively.

Statistically, it seemed that there was no trans-callosal supression caused by unilateral brain tu-mors. However the ΔrCBF of the mirror foci in postoperative patients decreased significantly. In conclusion, the remote effects on the cereb-ral blood flow, which are common in strokes cases, were demonstrated in many cases of supratento-rial brain tumors and the occurrence of CCH was closely related to the frontoparietal lesion in-cluding the tumor and peritumoral edema. Also the mechanism of CCH was discussed with preference for a transneural supression.


Copyright © 1989, Igaku-Shoin Ltd. All rights reserved.

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電子版ISSN 2185-405X 印刷版ISSN 0006-8969 医学書院

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