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Nasal Colltinuous Positive Airway Pressure (nCPAP) Treatment Using a Split-night Protocol for Sleep Breathing Disorder Yoshihiro Yamashiro 1 , Yasuaki Suganuma 1 , Takashi Miyasaka 1 , Kimio Hosaka , Kou Uchida 1 1Second Department of Internal Medicine, Toho University School of Medicine Keyword: 睡眠呼吸障害 , 経鼻的持続的陽圧呼吸 , split-night法 , sleep breathing disorders , nasal continuous positive airway pressure , split-night protocol pp.1011-1014
Published Date 1997/10/15
DOI https://doi.org/10.11477/mf.1404901573

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  • Abstract
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Nasal continuous positive airway pressure (CPAP) treatment for obstructive sleep apnea (OSA) is generally applied on the second night following the diagnostic polysomnography (PSG) on the first night. Diagnosis and treatment in one-night PSG would be cost effective and labor saving, if it were showen to be effective. We used a split-night protocol for 32 patients with sleep breath-ing disorder, namely a diagnosis was made in the first half of the night, and CPAP titration was carried out in the latter half. 32 patients (30 males, two females, mean age was 47.4±11.2 years, mean body mass index was 28.6±4.7kg/m2) who were suspected of having OSA were studied, using a standard 8 hours of PSG with snoring sound and pretibialis EMG.

In the first half of the night, after one or two REM periods. apnea hypopnea index (AHI) was calculated, and CPAP was attached to the patients when AHI> 10 was reached. Even when there was AHI <10, CPAP was attached if the breathing-disorder-related arousal index (B‐Arl)-> 10. AHI was significantly reduced from (52.9±31.5/hr) in the first half of the night to (5.8±11.9/ hr, p<0.001) in the latter half of the night. Desaturation index decreased from 51.7±33.0/hr to 3.3±3.9/hr (p<0.001). B-ArI was also reduced from 51.9±2.8/hr to 7.0.±7.5/hr (p<0.001). Sleep parameters were improved in the latter half. For example, sleep efficiency index (TST/ TRT) increased, awakenings and stage 1 decreased, and stage REM increased significantly. We concluded that split-night protocol may be useful for the CPAP treat-ment for sleep breathing disorders.


Copyright © 1997, Igaku-Shoin Ltd. All rights reserved.

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電子版ISSN 1882-1200 印刷版ISSN 0452-3458 医学書院

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