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Clinicopathologic study of acute coronary occlusion in percutaneous transluminal coronary angioplasty Tsuneo Hoshino 1 , Hiroshi Yoshida 1 , Naohisa Noda 1 , Takehiko Yamada 1 , Ryoji Ozono 1 , Shoichi Yokoyama 1 , Noriko Mori 1 , Tsuneo Kaburagi 1 1Department of Cardiology, Shizuoka General Hospital pp.435-441
Published Date 1989/4/15
DOI https://doi.org/10.11477/mf.1404205461

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  • Abstract
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Twenty-four patients with acute coronary occlu-sion (ACO) within 24 hours after percutaneous transluminal coronary angioplasty (PTCA) were re-viewed and compared with a control group of 86 consecutive patients who underwent successful first PTCA and had no ACO.

ACO occurred within 40 min (mean 15.7 min) after PTCA in 22 patients and more than 12 hours in 2. The group with ACO had a significantly higher incidence of female (46% vs 23%), acute myocardial infarction (63% vs 35%), eccentric les-ions (73% vs 28%), tortuous lesions (30% vs 4%) and coronary dissection or intraluminal haziness (89% vs 34%). Luminal narrowing before and after PTCA was significantly higher in ACO group than in control group (93% and 56% vs 87% and 23%). Repeat PTCA was performed in 17 patients andwas successful in 13. Coronary bypass surgery was performed in 4 patients. Intracoronary urokinase was ineffective to ACO. In 3 autopsy cases dying 5, 14 and 17 days after PTCA, large extent of in-timal tears and thrombus in the space of tears and the lumens were observed.

These results suggest that coronary dissection chiefly contributes to ACO and coronary thrombosis is superimposed for a secondary event in most of cases with ACO.


Copyright © 1989, Igaku-Shoin Ltd. All rights reserved.

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電子版ISSN 1882-1200 印刷版ISSN 0452-3458 医学書院

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