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Endoscopic Diagnosis of Superficial Oral Cancer Chikatoshi Katada 1 , Hirokazu Higuchi 2 , Yo Kishimoto 3 , Takahiro Shimizu 4 , Mitsuhiro Nikaido 4 , Takahiro Inoue 4 , Akira Yokoyama 1 , Masashi Tamaoki 1 , Motoo Nomura 1 , Yosuke Mitani 1 , Yuki Kondo 1 , Hiroaki Ito 5 , Sachiko Minamiguchi 5 , Hironori Haga 5 , Yasuaki Furue 6 , Hiroshi Hosono 7 , Koichi Kano 7 , Shinya Ohashi 1 , Manabu Muto 1 1Department of Clinical Oncology, Kyoto University Hospital, Kyoto, Japan 2Department of Medical Equipment, Kyoto University Hospital, Kyoto, Japan 3Department of Otolaryngology-Head and Neck Surgery, Kyoto University Hospital, Kyoto, Japan 4Department of Gastroenterology and Hepatology, Kyoto University Hospital, Kyoto, Japan 5Department of Diagnostic Pathology, Kyoto University Hospital, Kyoto, Japan 6Department of Gasroenterology, Kitasato University Hospital, Sagamihara, Japan 7Department of Otorhinolaryngology-Head and Neck Surgery, Kitasato University Hospital, Sagamihara, Japan Keyword: 口腔癌 , 表在癌 , NBI , TXI , 拡大内視鏡 pp.1112-1119
Published Date 2023/9/25
DOI https://doi.org/10.11477/mf.1403203315

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  • Abstract
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 Oral cancer has higher incidence and mortality rates than laryngeal, oropharyngeal, and hypopharyngeal cancers. It often occurs before and after esophageal or head and neck cancer treatment as a field cancerization phenomenon. The Japan Esophageal Cohort study is a prospective cohort study that enrolls patients with esophageal cancer after endoscopic resection. Esophageal or head and neck endoscopic examinations were repeated every 6 months. Local examinations to detect head and neck cancer by an otolaryngologist were repeated every 12 months. The 2-year cumulative incidence of metachronous head and neck cancer was 3.7%. An otolaryngologist detected one patient with superficial head and neck cancer originating from the hard palate. Narrow-band imaging magnifying endoscopy of 112 patients with esophageal cancer undergoing head and neck screening in a prospective study revealed two patients with superficial cancers on the tongue and one on the hard palate. Appropriate endoscopic oral cavity observation and surveillance should be established for early detection to help improve the prognosis and quality of life in patients with oral cancer.


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電子版ISSN 1882-1219 印刷版ISSN 0536-2180 医学書院

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