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The Characteristics of Progression of Colorectal Cancers from the Point of Epidemiology and Mass Screening Yasushi Oda 1 , Eisuke Kaku 1,2 , Hideyo Goto 1 , Kiwamu Hasuda 1 , Tomofumi Tanaka 1 , Makoto Yasunaga 1 , Kiyoharu Ito 3 , Hisashi Okubo 1 , Masahiro Hattori 1 , Takahiro Fujimori 4 , Yutaka Sasaki 2 1Hattori GI Endoscopy and Oncology Clinic, Kumamoto, Japan 2Department of Gastroenterology and Hepatology, Graduate School of Medical Science, Kumamoto University, Kumamoto, Japan 3Ozaki Clinic, Kumamoto, Japan 4Department of Surgical and Molecular Pathology, Dokkyo Medical University School of Medicine, Tochigi, Japan Keyword: 一般人口 , advanced neoplasia , nonpolypoid growth pattern , 早期癌 , 陥凹型 pp.1884-1890
Published Date 2008/12/25
DOI https://doi.org/10.11477/mf.1403101532

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 Subjects were people 40-79 years of age who underwent first colonoscopy for screening. Among the lesions detected, advanced neoplasias were examined. The proportion of each morphological appearance among advanced neoplasias excluding T2 or more advanced colorectal cancers, were examined. Final study subjects were 8,270 people. Six hundred cases of advanced neoplasia was detected in 7.9% of men, of 3.8% in women. Polyp-type occupied 75%. Nonpolypoid type and laterally spreading tumor occupied 7% (one third of which were depressed type), and 18%, respectively. Estimations of origins were examined among early colorectal cancers detected in 14,817 subjects. The lesions which showed both nonpolypoid growth pattern and no adenomatous components in histology were estimated as de novo cancers. De novo cancers were found in 18.6% of men and 27.4% of women.


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電子版ISSN 1882-1219 印刷版ISSN 0536-2180 医学書院

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