汎発性膿疱性乾癬との鑑別を要した小児に生じた角層下膿疱症

・小児の顔面，四肢に生じた角層下膿疱症を経験した．

・抗ヒスタミン薬と外用ステロイドで改善した．

・膿疱性乾癬との鑑別を要したためIL36RN遺伝子の変異解析を行ったが，異常はなかった．

・小児の角層下膿疱症の報告は，本邦では2例目と思われる．

（「症例のポイント」より）

　

A case of subcorneal pustular dermatosis in an infant that required differentiation from generalized pustular psoriasis

　

Hanamura, Takuya1）Inoue, Yuuki3）Asai, Rirei4）Mizuta, Miyuki2）Aiyama, Akiteru5）Mitsuma, Teruyuki2） 1）Department of Dermatology, Toyohashi Municipal Hospital 2）Department of Dermatology, Ichinomiya Municipal Hospital 3）Department of Dermatology, Japanese Red Cross Nagoya Daiichi Hospital 4）Department of Dermatology, Matsunami General Hospital 5）Department of Dermatology, Nissin Orido Hospital

　

Subcorneal pustular dermatosis is a rare pustular eruption which is usually developed in middle-aged women and rarely during childhood. Here, we report a pediatric case of subcorneal pustular dermatosis which generalized pustular psoriasis must be differentiated. On the basis of the lack of IL36RN mutation, we were able to diagnose this case as subcorneal pustular dermatosis.