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・乳幼児期に発症した難治性の凍瘡の症例を経験した.
・凍瘡の治療は一般的には対症療法であり寒冷刺激を避け,保湿剤などで対症療法を行う.
・難治性の場合,凍瘡様皮疹をきたすさまざまな疾患を鑑別することが重要である.
(「症例のポイント」より)
Differential diagnosis of refractory chilblain in infancy
Ebato, Takasuke1)Bando, Yuki2) 1)Department of Pediatrics, Kitasato University School of medicine 2)Department of Pediatrics, Kitasato University Medical Center
A 1-year old boy developed many small erythema and ulcers on his paw and toes in winter. Histological examination revealed inflammatory cells mainly lymphocytes infiltrated around the vascular of the dermis, and the papillary dermis changed edematous. Those findings were consistent with pathogenesis of chilblain. The many evaluations were performed because the symptom was persistent with treatment and he had family history of chilblain. So far he was not diagnosed with auto-inflammatory diseases, however it should be necessary to careful observation.
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