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Colorectal ESD: history of development and recent advances Naohisa YAHAGI 1 1Division of Research and Development of Minimally Invasive Treatment, Cancer Center, Keio University School of Medicine, Tokyo, Japan Keyword: colorectum , endoscopic submucosal dissection (ESD) , development pp.1603-1608
Published Date 2022/10/25
DOI https://doi.org/10.24479/endo.0000000482
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 Endoscopic resection of gastrointestinal tumors is a typical minimally invasive treatment technique that allows preservation of organ function. However, until the late 1990s, only polypectomy or EMR existed, and treatable lesions with those techniques were very limited. To expand the capacity of endoscopic resection, a new technique which consisted of mucosal incision and submucosal dissection was developed based on various ideas. Among them, our concept was to “form a sufficient elevation by local injection and then incise and dissect only the safe portion under direct vision with a blunt ended short needle knife”, which could be performed in the colon without any problem. Although there was a lot of criticism at the beginning, it was gradually accepted through the promotion of the concept of maintaining safety and the development of new devices. Since colorectal ESD achieved relatively good treatment results, it was covered by the insurance system in Japan and became a widespread procedure. Currently, this technique is gradually gaining attention and spreading throughout the world.


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電子版ISSN 印刷版ISSN 0915-3217 東京医学社

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