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Transdisciplinary Approach for Sarcopenia. The effects of exercise on skeletal muscle hypertrophy and satellite cells. Fujimaki Shin 1 , Takemasa Tohru 2 , Kuwabara Tomoko 3 1Research Center for Stem Cell Engineering, National Institute of Advanced Industrial Science and Technology, Japan./Physical Education, Health and Sport Sciences, Graduate School of Comprehensive Human Sciences, University of Tsukuba, Japan. 2Physical Education, Health and Sport Sciences, Graduate School of Comprehensive Human Sciences, University of Tsukuba, Japan. 3Research Center for Stem Cell Engineering, National Institute of Advanced Industrial Science and Technology, Japan. pp.1463-1470
Published Date 2014/9/28
DOI https://doi.org/10.20837/4201410035
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 Skeletal muscle has a high degree of plasticity. The mass of skeletal muscle maintains owing to muscle protein synthesis and the regeneration by satellite cells. Skeletal muscle atrophy with aging(sarcopenia)is developed by decline of muscle protein synthesis and dysfunction of satellite cells. It is urgently necessary for today's highly aged society to elucidate the mechanism of sarcopenia and to establish prevention measure. This review shows that the positive effects of “exercise” on muscle protein synthesis and satellite cell function including their main molecular mechanism.



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電子版ISSN 印刷版ISSN 0917-5857 医薬ジャーナル社

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