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Perioperative Coagulation Management;Up-to-Date:Preface and Comments Yoshifumi KOTAKE 1 1Department of Anesthesiology, Toho University Ohashi Medical Center Keyword: thromboembolism , anticoagulant , coagulopathy , coagulation factor concentrate pp.424-425
Published Date 2025/7/10
DOI https://doi.org/10.18916/masui.2025070004
  • Abstract
  • Reference

 The number of individuals with comorbidities such as cerebrovascular disease, pulmonary thromboembolism, and atrial fibrillation is increasing, and the number of patients undergoing surgery while taking preoperative anticoagulants is expected to continue to rise. In addition, the appropriate management of massive bleeding during surgery remains a critical challenge. New oral anticoagulants, their antagonists, and concentrated coagulation-factor products are increasingly used. A compilation of the latest information on these agents is thus desirable. In this special issue, anticoagulants and coagulation-factor products, concentrated fibrinogen preparations, concentrated prothrombin complex preparations, and recombinant active factorⅦpreparations are summarized.

 In the clinical section, the latest findings in cases requiring careful coagulation management―such as open-heart surgery, childbirth/cesarean section, and head trauma and intracranial bleeding―are presented by specialists. The latest findings regarding the management of perioperative coagulation are also summarized. Due to space limitations, this thematic series does not cover regional anesthesia in patients who are on anticoagulant therapy or coagulation abnormalities and their management in sepsis patients. For the latest reviews on these topics, please refer to the following references.


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電子版ISSN 印刷版ISSN 0021-4892 克誠堂出版

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