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本特集にて他の先生方が書かれているとおり,脳腫瘍の診療において,再発と治療後変化との鑑別は非常に重要な課題である1)。数十年にわたって期待され,多くの研究がされてきたにもかかわらず,いまだに決定的な方法が見つからない,いわゆるアンメットメディカルニーズである2)。
Nuclear medicine is a technique that can be used for both diagnosis and treatment. FDG PET is a widely used technique as an in-vivo image of cancer, but its physiological accumulation in normal brain tissue is problematic especially for brain tumor imaging. 11C-methionine overcomes this disadvantage, but has different drawbacks such as a short half-life. Although nuclear medicine therapy for brain tumors is still in the clinical trial stage, several radiopharmaceuticals, including beta and alpha emitters, are expected to be used for the treatment of brain tumors in the future.
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