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Japanese

Thymoma with Pure Red-cell Aplasia and Hypogammaglobulinemia Minoru Yamaki 1 , Mai Nishina 1 , Toshio Noriyuki 1 , Syuji Yonehara 1 1Department of General Thoracic Surgery, Onomichi General Hospital Keyword: thymoma , pure red-cell aplasia , hypogammaglobulinemia pp.115-118
Published Date 2023/2/1
DOI https://doi.org/10.15106/j_kyobu76_115
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Thymoma presenting concurrent pure red-cell aplasia (PRCA) and hypogammaglobulinemia are extremely rare. A 67-year-old woman with a short of breath was referred to our hospital due to anemia and the chest abnormal shadow. Laboratory investigations revealed a hemoglobin level of 5.6 g/dl and reticulocyte percentage of 0.2%. Her serum gamma-globulin level was low. Chest computed tomography (CT) revealed a 7-cm tumor in the left upper mediastinum. We diagnosed the patient with thymoma accompanied by PRCA and hypogammaglobulinemia. The patient underwent thymectomy and PRCA has been successfully treated by postoperative cyclosporine administration. Monthly intravenous infusion of gamma-globulin has been necessary for the control of hypogammaglobulinemia. Currently, she is doing well without recurrence of thymoma or PRCA five years after the surgery.


© Nankodo Co., Ltd., 2023

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電子版ISSN 2432-9436 印刷版ISSN 0021-5252 南江堂

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