CA19-9産生肺粘液・非粘液混合腺癌の1例

CA19-9 Producing Mixed Invasive Mucinous and Non-mucinous Adenocarcinoma；Report of a Case

はじめに　CA19-9産生肺癌の多くは粘液産生性の腺癌であり，また，発見時には進行例が多く予後不良である．われわれは，術前に血清CA19-9高値を認め，組織学的に腫瘍よりCA19-9産生が確認された粘液・非粘液混合腺癌の1例を経験したので報告する．

A 66-year-old woman was referred to our hospital due to the abnormal shadow on chest X-ray. Computed tomography （CT） scan revealed a mass in the lower lobe of the right lung and the serum CA19-9 level was 1,600 U/ml. Under the diagnosis of adenocarcinoma by bronchoscopic brushing cytology, right lower lobectomy with mediastinal lymph node dissection was performed. Histopathological examination showed mixed invasive mucinous and non-mucinous adenocarcinoma ［World Health Organization （WHO） 8th］ of stage IA3 with T1cN0M0 ［Union for International Cancer Control （UICC） 8th］. Immunohistochemically, the tumor cells were stained positively for CA19-9. Postoperative course was uneventful and the CA19-9 level decreased to 35.5 U/ml 2 months after operation.