Typical Carcinoid of the Lung with Abnormal Elevation of Serum Pro-gastrin-releasing Peptide (ProGRP) Hiroshi Hashimoto 1 , Yuichi Ozeki 1 , Kouji Kameda 1 , Shinichi Taguchi 1 1Department of Thoracic Surgery, National Defense Medical Callege Keyword: pulmonary carcinoid , typical carcinoid , pro-gastrin-releasing peptide (ProGRP) pp.593-596
Published Date 2018/8/1
DOI https://doi.org/10.15106/j_kyobu71_593
  • Abstract
  • Look Inside
  • Reference

A 40-year-old male was referred to our hospital because of a nodular shadow detected in the left lower lobe with the tendency to increase gently. Because fluoro-2-deoxy-D-glucose (FDG) uptake was extremely low on a FDG positron emission tomography (PET-CT), the tumor was highly suspected of the benign tumor. Five years later, a follow-up computed tomography (CT) showed the shadow to be enlarged. FDG uptake was changed to be high, and serum level of pro-gastrin-releasing peptide (ProGRP) was extremely elevated. Surgical treatment was chosen under suspicious diagnosis of neuroendocrine tumor, such as small cell carcinoma, large cell neuroendocrine carcinoma, and carcinoid. By the intraoperative aspiration cytology, a small cell carcinoma or a carcinoid was suspected and left lower lobectomy with systemic lymph node dissection was performed. The final histological diagnosis was a typical carcinoid. The elevated serum ProGRP immediately decreased to normal postoperatively.

© Nankodo Co., Ltd., 2018


電子版ISSN 2432-9436 印刷版ISSN 0021-5252 南江堂