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Vocal function after (chemo-)radiotherapy for early glottic cancer Yoshie Iino 1,2 , Koichiro Saito 2,3 , Tetsuya Tsuji 4 , Ryuichi Hayashi 1,5 1Department of Musculoskeletal Oncology and Rehabilitation, National Cancer Center Hospital East 2Department of Otolaryngology-Head and Neck Surgery, Keio University School of Medicine 3Department of Otolaryngology-Head and Neck Surgery, Kyorin University School of Medicine 4Department of Rehabilitation Medicine, Keio University School of Medicine 5Department of Head and Neck Surgery, National Cancer Center Hospital East Keyword: 放射線治療 , 化学放射線療法 , 声門癌 , 音声機能 , 有害事象 , radiotherapy , chemo-radiotherapy , glottic cancer , vocal function , adverse effect pp.56-64
Published Date 2017/3/15
DOI https://doi.org/10.11477/mf.6001200115
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 While (chemo-)radiotherapy ((C)RTx) is one of the established therapeutic options for head and neck cancer, well-refined management of unavoidable adverse reactions is indispensable to provide better medical care. The purpose of this study was to assess the post-therapeutic vocal function of the patients who underwent (C)RTx to treat their glottic cancer. Thirty-four patients with early glottic cancer (T1, n=17;T2, n=17) took part in this study. GRBAS scale, acoustic analyses, maximum phonation time (MPT), and laryngeal endoscopic findings were used as objective vocal parameters, while voice handicap index (VHI) was utilized for subjective vocal assessment. Vocal evaluations started 3 months after (C)RTx, and the post-therapeutic period was divided at 24 months and 48 months. VHI, MPT, and glottis closure showed the best scores in the 25-48 months group. Laryngeal web formation was considered as a factor that potentially impairs patients' vocal quality 49 months or more after surgery. Vocal quality of the T2 group was significantly more strained (p=0.001) compared with the T1 group. Around 1/3 of the patients showed divergence of the scores in the subjective and objective vocal assessment. Speech-language-hearing therapists should pay attention to endoscopic findings and oncological information of the patients to achieve satisfactory vocal function.


Copyright © 2017, Japanese Association of Speech-Language-Hearing Therapists. All rights reserved.

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電子版ISSN 印刷版ISSN 1349-5828 日本言語聴覚士協会

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