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Japanese

A general discussion of anesthetics Satoshi HAGIHIRA 1 1Department of Anesthesiology Kansai Medical University pp.625-632
Published Date 2021/10/1
DOI https://doi.org/10.11477/mf.3102200903
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It is essential that general anesthetics produce unconsciousness and amnesia, and that they allow restoration of the patient's normal state shortly after termination of administration, although there is no strict definition of “anesthetics”. Unlike most other drugs, anesthetics act on a large number of channels and receptors. At present, the mechanism for consciousness has not been clarified. Recently, Tononi's theory that consciousness is not located in a specific part of the brain, but rather in the connection of each part of the cerebral cortex, has gained acceptance. Anesthetics interrupt the inter-cortical connections and produce unconsciousness. Anesthetics suppress memory at concentrations lower than unconsciousness, but implicit memories can persist at even higher concentrations. Anesthetics do not have antinociceptive effects, therefore balanced anesthesia, a combination of anesthetics and analgesics, is used in clinical practice.


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電子版ISSN 2186-7852 印刷版ISSN 1883-4833 メディカル・サイエンス・インターナショナル

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