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Current state of multidrug-resistant Gram-negative bacilli Yoshichika Arakawa 1 1Department of Bacteriology, Nagoya University Graduate School of Medicine Keyword: 多剤耐性Gram陰性桿菌 , 新型カルバペネマーゼ , プラスミド媒介性多剤耐性遺伝子 pp.817-826
Published Date 2012/8/15
DOI https://doi.org/10.11477/mf.1542103091
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Various kinds of multidrug-resistant Gram-negative bacilli such as NDM-1-producing Klebsiella pneumoniae, multidrug-resistant Acinetobacter, OXA-48 or KPC-type carbapenemase-producing K. pneumoniae, and oxyimino cephalosporin/fruoroquinolone resistant Escherichia coli have emerged and spread worldwide, together with ESBL-producing K. pneumoniae and E. coli, MBL-producing Gram-negative rods, and multidrug-resistant Pseudomonas aeruginosa. Since antimicrobial agents effective for these multidrug-resistant pathogenic bacilli are very limited and only a few new drugs are under development, we should block their further global spread by identifying them early and performing efficacious infection control measures.


Copyright © 2012, Igaku-Shoin Ltd. All rights reserved.

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電子版ISSN 1882-1367 印刷版ISSN 0485-1420 医学書院

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