オスラー病症例—Hereditary hemorrhagic telangiectasia

OSLER'S DISEASE HEREDITARY HEMORRHAGIC TELANGIECTASIA

　I．はじめに

　鼻出血を主訴とする疾患は数多くみられるが，数十年にわたる頑固な鼻出血は少なく，このような症例には鼻疾患の他に出血性素質，血液病などの全身的な原因を常に考慮に入れなければならない。著者は上記の症状を主訴とした稀なるオスラー病を経験したので報告する。患者は貧血を主訴に再々某大学，公立病院などに精査のため入院したが，本症の病態を指摘されずに，当科を訪れた。

　A case of Osler's disease in a woman, aged 72 is reported. The personal history revealed the patient affected with repeated epistaxis since her childhood but, recently, since a few years ago the hemorrhage had been profuse as to necessiate hospitalization. The hereditary influence was not conclusive.

　The telangiectasis is found in other areas of the body, such as, lips, tongue, the mucous membranes of the mouth, nose and stomach and in parts of the fingers.

　The growth on the inferior turbinate was treated by cauterization which was deemed inapplicable to those on the nasal septum. The latter was treated by means of estrogen therapy which appeared to be successful. At present, 2 months later there is no hemorrhage.