変形菌に依る広範なる耳性頭蓋内合併症々例

　耳性頭蓋内合併症は，従来我が領域に於ける重篤疾患として幾多の報告を見るが，殊に最近の化学療法の進展に伴い，本症の予後は著しく改善せられた。而し乍ら一方，之等の化学療怯にも一定の限界があり，起炎菌の如何によつては，各種抗生物質の発育阻止作用が，何れも顕著でない場合もあり得るのであつて，本症が今尚予断を許さぬ重篤疾患である事に変りはない。私は最近，左側慢性真珠腫性中耳炎にモルガン氏変形菌の感染を受け，電撃的に進展して広範な各種の頭蓋内合併症を惹起し，強力な諸種療法の施行にも拘らず，遂に鬼籍に入つた1例を経験し，更に剖検並びに細菌学的にも検討を加えて，その感を新にしたので茲に報告し，御批判を仰ぎたい。

Hirabayashi reports a case of mastoiditis where no form of treatment was able to save the pa-tient from death. In the history of the case, a boy-aged 11, has been affected with cholesteatoma si-nce the age of 2. With infection added to this condition the patient rapidly developed intrac-ranial involvements, meningitis, cerebral abcess and destruction of contiguous cerebral tissues. The patient died on the 27th day of hospitaliza-tion after all possible means surgical and me-dical had been adopted for the case. Infecting organisms were found to be Proteus Morgani which by sensitivity test towards antibiotics proved to be resistant. The author states that, from the experienced gained from the present case, the use of antibiotics is definitely limited in their application and should not be wholly de-pended upon as something which might bring cure to all forms of infections.