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pp.549-551
Published Date 1952/12/20
DOI https://doi.org/10.11477/mf.1492200794

 Goto observed that in maintaining muscular contractions in a nerve-muscle preparation saline solution is far superior in contrast to that of sodium bicarbonate. The specimen was prepared from the leg of a frog which weighed 20g.; stimulations were afforded by galvanic current which was interruptedly applied once every second while the preparation was repeatedly bathed in either 0.6 percent saline or 0.4 percent sodium bicarbonate solution as the case may be. In this way fatigue curves were obtained for both agents under the test. With clonic contractions the two agents showed no marked difference. But, in tonic contractions the saline solution far surpassed that of sodium bicarbonate in the period of time in which muscular actions were maintained.


Copyright © 1952, Igaku-Shoin Ltd. All rights reserved.

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電子版ISSN 印刷版ISSN 0386-9679 医学書院

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