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An Epithelial Cyst at the Frontal Convexity Osamu MOTOHASHI 1 , Motonobu KAMEYAMA 1 , Shigeki IMAIZUMI 1 , Masaki MINO 1 , Hiroshi NAGANUMA 2 , Takehide ONUMA 2 1Department of Neurosurgery, Sendai City Hospital 2Department of Pathology, Sendai City Hospital Keyword: epithelial cyst , supratentorial , electronmicroscopy , immunohistochemistry pp.857-862
Published Date 2001/9/10
DOI https://doi.org/10.11477/mf.1436902098
  • Abstract
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We report a rare case of an epithelial cyst at the right frontal convexity. A 60-year-old woman came to our hospital suffering from dysarthria and gait disturbance. Computed tomography (CT) of the brain on admission showed a round low-density area, 6 cm in diameter, at the right frontal convexity. Midline shift and displacement of the lateral ventricle are seen. There is no contrast enhancement effect. Excision of the cyst wall and fenestration into the subarachnoid space was carried out and the patient was discharged with no neurological deficits. After 5 years, regrowth of the cyst was seen. Cyst-peritoneal shunt was performed and she was discharged uneventfully. Light microscopy showed the cyst wall consisted of a monolayer of flat epithelium and loose connective tissue.

An electronmicrograph of the cyst wall showed a non-ciliated epithelial layer with microvilli and base-ment membrane. The epithelial cells connecting with each other through desmosome have numerous endo-plasmic reticulum and mitochondria . Interdigitation of the cytoplasmic membrane was not seen. The term “epithelial cyst” seems ambiguous. We discuss the pathogenesis and the nomenclature for intracranial be-nign cystic lesions based on the previous literature.


Copyright © 2001, Igaku-Shoin Ltd. All rights reserved.

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電子版ISSN 1882-1251 印刷版ISSN 0301-2603 医学書院

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