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Brain Surface Clear Cell Ependymoma : case report Kenta FUJIMOTO 1,4 , Hideyuki OHNISHI 1 , Naoki KOSHIMAE 1 , Yuki IDA 1 , Yukihide KANEMOTO 1 , Yasushi MOTOYAMA 1 , Masahiko TSUJIMOTO 2 , Kiyoshi TAKEMURA 3 1Departments of Neurosurgery, Osaka Police Hospital 2Departments of Pathology, Osaka Police Hospital 3Department of Neurosurgery, Ishinkai Yao General Hospital 4Department of Neurosurgery, Seikeikai Hospital Keyword: ependymoma , extra-parenchyma , brain surface , cyst , clear cell pp.843-846
Published Date 1999/9/10
DOI https://doi.org/10.11477/mf.1436901778
  • Abstract
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We report a case of brain surface clear cell ependymoma. A 13-year-old boy presented with complaintsof right hypesthesia. Computed tomography and magnetic resonance image showed a left fronto-parietalcystic, calcified mass lesion. He underwent total resection of the tumor including cyst wall. The tumor lo-cated on the surface of the parietal lobe was sharply demarcated from the surrounding brain tissue andthere was no continuity with the ventricular wall. Histological examination of the surgical specimensshowed oligoclendroglioma-like cells that had round unclei, clear cytoplasm which formed perivascularpseudorosettes, and immunoreactivity for glial fibrillary acidic protein (GFAP). Electromicroscopically,microvilli were seen. The findings were compatible with clear cell ependymoma. The cyst wall was linedwith a layer of single cuboidal cells and, immunohistochemically, had no basal membrane. The inner sur-face of the cyst was positive for EMA, and the cuboidal cells were positive for GFAP. We discuss possiblemechanisms for tumor growth in our case and the histogenesis of its cyst.


Copyright © 1999, Igaku-Shoin Ltd. All rights reserved.

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電子版ISSN 1882-1251 印刷版ISSN 0301-2603 医学書院

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