雑誌文献を検索します。書籍を検索する際には「書籍検索」を選択してください。

検索

書誌情報 詳細検索 by 医中誌

Japanese

An Enlarging Dysembryoplastic Neuroepithelial Tumor during a 6-year period : a case report Narihito YAMAGUCHI 1 , Hiroaki OHNISHI 1 , Osamu TACHIBANA 2 , Mitsuhiro HASEGAWA 2 , Takumi EMORI 3 1Department of Neurosurgery, Asanogawa General Hospital 2Department of Neurosurgery, Kanazawa University School of Medicine 3Department of Neurology, Asanogawa General Hospital Keyword: dysembryoplastic neuroepithelial tumor , MRI , pathology , epilepsy pp.1097-1101
Published Date 1998/12/10
DOI https://doi.org/10.11477/mf.1436901651
  • Abstract
  • Look Inside

A 16-year-old boy who had been found at the age of 9 years to have complex partial seizures was refer-red to our department by a psychiatrist for evaluation for surgical treatment of epilepsy, in 1994. A diagno-sis of multiple cerebral infarction accompanied with arachnoid cyst was made when he was 11 years old,in 1988, by computed tomography (CT) and magnetic resonance imaging (MRI) findings. Results of aneurological examination on admission revealed marked mental and speech retardation. MRI and CT stu-dies demonstrated an enlarged Sylvian fissure and a mass lesion in the left frontal lobe which was en-larged, compared to the findings of MRI in 1988. A left fronto-temporal craniotomy with excision of thefrontal lesion was performed. I listological examination revealed cortical dysplasia, multi-nodular pattern,and glioneuronal components, whose findings coincide with criteria for diagnosing dysembryoplasticneuroepithelial tumors. MIBI antibody immunostaining study revealed no positivity, but immunostainingstudy for PCNA (proliferation of cell nuclear antigen) revealed from 0 to 6.5% positivity in each nodule.PCNA high positivity was observed in the nodules which were composed of packed oligodendrocyte-likecells. Enlargement in the size of the lesion in our case suggests increased cell proliferation activity during a6-year period.


Copyright © 1998, Igaku-Shoin Ltd. All rights reserved.

基本情報

電子版ISSN 1882-1251 印刷版ISSN 0301-2603 医学書院

関連文献

もっと見る

文献を共有