雑誌文献を検索します。書籍を検索する際には「書籍検索」を選択してください。

Neurological Surgery No Shinkei Geka Volume 26, Issue 9 （September 1998）

Neurological Surgery 脳神経外科 26巻9号（1998年9月発行）

Japanese English

症例

硬膜との癒着を示した脳内原発Malignant Fibrous Histiocytomaの1例 Primary Intracerebral Malignant Fibrous Histiocytoma with Adhesion to a Dura : a case report 藤原和則 ¹ , 上之原広司 ¹ , 鈴木晋介 ¹ , 鈴木博義 ² , 荒井啓晶 ¹ , 西野晶子 ¹ , 桜井芳明 ¹ Kazunori FUJIWARA ¹ , Hiroshi UENOHARA ¹ , Shinsuke SUZUKI ¹ , Hiroyoshi SUZUKI ² , Hiroaki ARAI ¹ , Akiko NISHINO ¹ , Yoshiharu SAKURAI ¹ ¹国立仙台病院脳神経外科 ²国立仙台病院臨床検査科 ¹Department of Neurosurgery, Sendai National Hospital ²Department of Pathology and Laboratory Medicine, Sendai National Hospital キーワード： malignant fibrous histiocytoma , intracerebral , Ki-67 Keyword: malignant fibrous histiocytoma , intracerebral , Ki-67 pp.837-844

発行日 1998年9月10日 Published Date 1998/9/10

DOI https://doi.org/10.11477/mf.1436901617

PDF(9241KB)

有料閲覧

Abstract 文献概要
1ページ目 Look Inside

I．はじめに

　Malignant fibrous histiocytoma（MFH）は，軟部組織のsarcomaでは最も多く，10.5-34％を占め，四肢，後腹膜に好発する^4,6,29）．一方，頭蓋内原発のMFHは，1976年にGonzalez-Vitaleらによって初めて報告されたが^8），いまだ文献上散見するのみであり，極めて稀と思われる．今回，我々は，興味ある発育形態を示した頭蓋内原発MFHの1例を経験したので，若干の文献的考察を加えて報告する．

A case of malignant fibrous histiocytoma (MFH) in a 29-year-old man was reported. CT scans revealedan iso density mass which was homogeneously enhanced by contrast medium. MRI demonstrated that theright frontal tumor showed slight low signal intensity in T1-weighted image, and iso signal intensity inT2-weighted image. Gadolinium-enhanced T1-weighted image showed a homogeneously enhanced multi-nodular tumor. Right carotid angiogram revealed a tumor stain fed by the precentral artery. On operation,en-bloc resection was performed successfully. Postoperatively, local irradiation of 60Gy was performed.Microscopically, fibroblast-like cells arranged in storiform pattern were observed, and bizarre multinucleat-ed giant cells were also observed. Ki-67 labelling index was 54%. We considered the tumor was a MFHand arose from an intracerebral mesenchymal tissue. We reviewed some literature and briefly discussed cli-nicopathological features and therapy of intracranial MFH.