雑誌文献を検索します。書籍を検索する際には「書籍検索」を選択してください。

検索

書誌情報 詳細検索 by 医中誌

Japanese

Glioma Cell Biology Kensuke TATEISHI 1 1Department of Neurosurgery, Yokohama City University School of Medicine Keyword: グリオーマ , グリオーマ始原細胞 , 細胞起源 , 遺伝子異常 , 腫瘍内不均一性 , glioma , brain tumor-initiating cells , cell of origin , genomic characterization , tumor heterogeneity pp.476-484
Published Date 2021/5/10
DOI https://doi.org/10.11477/mf.1436204419
  • Abstract
  • Look Inside
  • Reference

 In this review, I summarized the biology of gliomas. Through past clinical and basic studies, I reviewed the evidence of the cell of origin of gliomas and the presence of brain tumor-initiating cells in gliomas, which are driven by multiple genomic alterations. In addition, the complicated tumor heterogeneity and neuronal-glioma network were studied. These mechanisms may underlie the treatment resistance and poor prognosis and support the identification of novel therapeutic targets for gliomas.


Copyright © 2021, Igaku-Shoin Ltd. All rights reserved.

基本情報

電子版ISSN 1882-1251 印刷版ISSN 0301-2603 医学書院

関連文献

もっと見る

文献を共有