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The Latest Glioma Surgical Support Devices and Intraoperative Applications of MRI Taichi SAITO 1,2 , Yoshihiro MURAGAKI 1 1Institute of Advanced Biomedical Engineering and Science, Faculty of Advanced Techno-Surgery, Tokyo Women's Medical University 2Department of Neurosurgery, Tokyo Women's Medical University Keyword: グリオーマ , 術中MRI , 術中フローサイトメトリー , 光線力学的療法 , スマート治療室 , glioma , intraoperative MRI , intraoperative flow cytometry , photodynamic therapy , Smart Cyber Operating Theater , SCOT pp.549-555
Published Date 2021/5/10
DOI https://doi.org/10.11477/mf.1436204428
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 We previously proposed an information-guided surgery based on objective intraoperative information to achieve a high precision and maximum resection of gliomas. In 2000, an “intelligent operating room” was constructed and put into operation as a place to train new “eyes,” “hands,” and “brains” for surgeons. Based on the positive experience from this room, it was subsequently developed into the Smart Cyber Operating Theater (SCOT), and from October 2019, Hyper SCOT was introduced at Tokyo Women's Medical University Hospital. This report introduces the latest surgical support devices that we have implemented in glioma surgery with Hyper SCOT.

 As an intraoperative image information support device, intraoperative MRI can correct brain shift, visualize residual tumor, and aid in performing maximal tumor resection, thereby greatly contributing to surgical results.

 As an intraoperative histological information support device, intraoperative flow cytometry can evaluate the presence of tumor cells and malignancy based on the measurement of the amount of DNA in tumor cells, and also predict the prognosis intraoperatively.

 Photodynamic therapy has been shown to be effective in clinical trials as an intraoperative treatment support device, and it is covered by insurance. Therefore, it is expected to be established as a standard treatment method for primary glioblastoma patients.


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電子版ISSN 1882-1251 印刷版ISSN 0301-2603 医学書院

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