脳原発悪性リンパ腫の腫瘍血管の超微形態

Ultrastructure of Capillary Permeability in Malignant Lymphoma

I．はじめに

　脳原発悪性リンパ腫の腫瘍血管について他の脳腫瘍と超微形態学的に比較，検討を行った．

The ultrastructure of the blood vessels of primary central nervous system malignant lymphoma was stu-died and compared with those in glial, non-glial and metastatic brain tumors. Five surgical specimens were studied by conventional ultrathin section and freeze-fracture replica techniques. Tumor vessels of various sizes were found. The luminal surfaces of the tumor vessels were irregular and the basal lamina had mul- tiple-layer structure. The perivascular spaces were en- larged and infiltrated with tumor cells. The endothe-lium had marked infoldings, increased pinocytotic ve- sicles and fenestrations.