脳腫瘍血管透過性の超微形態—播種，転移性髄芽腫の腫瘍血管

Ultrastructure of Capillary Permeability in Human Brain Tumor: Disseminated and metastatic medulloblastoma

I．はじめに

　髄芽腫は髄腔内播種を生じやすく，最終的には約半数に認めるといわれている．また，骨やリンパ節等の遠隔臓器にも転移しやすいことが知られている．そこで髄芽腫の原発巣と髄腔内播種巣およびリンパ節転移巣の腫瘍血管について，超微形態学的に観察し，比較検討を行った．

Abstract

The ultrastructure of the tumor vessels of primary cerebellar, subarachnoidal disseminated and extraneural metastatic medulloblastomas was studied. They were compared with those in glial, nonglial and metastatic brain tumors which have been previously reported. Twelve surgical specimens were examined. Seven tumors were limited to the vermin, the floor of the fourth ventricle and the cerebellar hemispheres. Four gross nodule seedings were demonstrated in the cere-bral and spinal subarachnoid space. One metastasis was demonstrated in the subclavicular lymph node.