骨増殖性変化を示した肺癌の頭蓋骨転移の1例

A Case of Osteoblastic Skull Metastasis of Lung Cancer

I．はじめに

　悪性腫瘍の骨転移は原発巣の治療が進歩し，生存期間が延長されるにつれ，近年増加の一途をたどっている．骨転移を好む悪性腫瘍は肺癌，乳癌，大腸癌，膀胱癌などである．そのうち肺癌の骨転移は一般的に骨破壊型であり，骨増殖型転移を示すものは極めて稀でわれわれの調べ得た範囲では報告例はみあたらない．今回骨増殖型頭蓋骨転移を認めた肺腺癌の1例を経験したので骨転移様式を中心に文献的考察を加えて報告する．

A case of osteoblastic skull metastasis of lung cancer is reported. A 56-year-old female patient was admitted to our hospital with complaints of headache and tumor of the right parietal hone. A plain skull X-ray showed hyperostotic feature of the right parietal bone. CT scan displayed that right parietal bone became thick and osteoblastic. Soft tissue was shown in the hyperostotic bone under MRI. An external carotid angiogram showed that the skull tumor was fed by the middle meningeal artery. The skull tumor and 2 solid in-tracerebral tumors were extirpated.