Werner症候群に合併した多発性髄膜腫の1例

Multiple Meningiomas with Werner's Syndrome: A case report

I．はじめに

　1904年Wernerによって最初に報告されたWerner症候群は，老人性顔貌・若年性白髪・若年性白内障などの早老症状を主症状とする疾患であり，文献的にかなり多くの報告例がみられるが，脳神経外科領域での報告は少ない．今回われわれは，多発性髄膜腫を伴った本症候群症例を経験したので，文献的考察を加え報告する．

A case of multiple meningiomas with Werner's syn-drome is reported. He was 45-year-old man, who com-plained change of character and slight right motor weakness for 4 months. His symptoms were character-istic small stature, premature senility, scleroderma-like changes and other manifestations. Glucose tolerance test showed a diabetic pattern. CT scan and cerebral angiography revealed multiple meningiomas. After che-mical embolization of the feeding artery, we removed these meningiomas successfully. We also reviewed the literature on Werner's syndrome with meningioma.