8歳女児にみられた成長ホルモン産生下垂体腺腫の1例

Growth Hormone Producing Pituitary Adenoma in an 8-year-old Girl: Case report

I．はじめに

　小児期における下垂体腺腫は稀であり，成人と比べその特殊性，特に治療の特殊性について充分考慮しておく必要がある．今回われわれは8歳女児に見られた成長ホルモンおよびプロラクチン産生下垂体腺腫の1例について報告するとともに文献的に検討した．

A rare case of pituitary adenoma in childhood presenting as giantism is reported.

A 6-year-old girl came to our attension in 1982 because of excessive growth noted since the age of 3 yr. Her appearance revealed giantism. She also had a 4 year history of genital bleeding, but no development of external genitalia nor mammary gland. Endocri-nological studies revealed markedly elevated serum basal levels of both growth hormone (GH) and prolactin (PRL). She had a bromocriptine therapy for 1 year and 8 months, but it was difficult to suppress her excessive growth rate.