Pituitary Apoplexyを起こした巨大下垂体腺腫

Pituitary Apoplexy of Giant Pituitary Adenoma:Case Report

Ⅰ．はじめに

　Pituitary apoplexyは一般に脳下垂体腫瘍において腫瘍内出血が起こり，そのために臨床症状の急激な発症，増悪を意味するclinical termである^4）．われわれは20年の長期の経過の後，突然重篤状態で発症し，主にnasopharyngeal extensionを呈していた巨大下垂体腺腫を経験したので臨床経過，剖検所見について報告し，あわせて若干の文献的考察を加えた．

Pituitary apoplexy, characterized by sudden onset or acute progression of signs and symptoms of pituitary adenoma, is rare yet well-known. One such case is presented with clinical course, neuroradiological findings and autopsy.

A 53-year-old female complained of sudden onset of severe headache, and rapidly deteriorated in the level of consciousness. Five days later, she became comatose and was admitted to National Sendai Hospital. Plain skull films and carotid angiograms revealed a remarkably large mass in the pituitary fossa. Death came ten hours after admission.