Symptomatic Seizure Associated with Takotsubo Cardiomyopathy: A Case Report Koichi KATO 1 , Masahiro ASAMI 1 , Hiroshi WANIFUCHI 1 1Department of Neurosurgery, Saitamaken Saiseikai Kurihashi Hospital Keyword: cerebral infarction , sudden unexplained death in epilepsy , symptomatic seizure , takotsubo cardiomyopathy , valproic acid pp.1039-1043
Published Date 2014/11/10
DOI https://doi.org/10.11477/mf.1436200030
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 A 68-year-old woman was admitted for symptomatic seizure. She had a history of cerebral infarction in the right fronto-temporal lobes, and was medicated for the symptomatic seizure with valproic acid. Her electrocardiogram(EEG)showed ST-segment elevation in leads II, III, aVF, and V2-V6. Emergency coronary angiography showed normal coronary arteries, however, left ventriculography showed apical ballooning in the systolic phase. She had no chest pain or dyspnea, and takotsubo cardiomyopathy was diagnosed due to ECG abnormality. The majority of the takotusbo cardiomyopathy patients recover rapidly, but in some the condition proves fatal. Seizure-associated takotsubo cardiomyopathy may cause sudden unexplained death in epilepsy(SUDEP), and EEG measurements should be carefully checked for seizure patients.

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