Neurological Surgery No Shinkei Geka Volume 32, Issue 10 (October 2004)
Japanese

Case Report of Rosai-Dorfman Disease Mimicking Pachymeningitis Yoshimasa KINOSHITA 1 , Hideoki YASUKOUCHI 1 , Eichi TSURU 1 , Rin YAMAGUCHI 2 1Department of Neurosurgery,Munakata Suikokai General Hospital 2Department of Pathology,Kurume University Keyword: Rosai-Dorfman disease , emperipolesis , dura pp.1051-1056
Published Date 2004/10/1
DOI https://doi.org/10.11477/mf.1436100495
  • Abstract
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 Rosai-Dorfman disease (RDD) is a rare idiopathic histioproliferative disease affecting the lymph nodes. Extranodal sites may be involved and occasionally represent the initial or sole manifestation of the disease. Central nervous system manifestations especially are exceedingly rare. We reported a case of isolated,intracranial,dural-based RDD. A 69-year-old male,admitted with a second generalized convulsion,was examined by high-resolution MR images that revealed a thickened,stratified dura in the left frontal region with associated cortical edema. The patient underwent craniotomy with subtotal resection of the lesion. Microscopically,with the cytoplasmic staining against S-100 protein the lesion was shown to consist of proliferative histiocytes exhibiting emperipolesis . The histopathological diagnosis was compatible with RDD. The diagnosis of RDD mimicking pachymeningitis is presented,and the previous reported cases of intracranial RDD are reviewed


Copyright © 2004, Igaku-Shoin Ltd. All rights reserved.

基本情報

03012603.32.10.jpg
Neurological Surgery 脳神経外科
32巻10号 (2004年10月)
電子版ISSN 1882-1251 印刷版ISSN 0301-2603 医学書院

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