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Precursors of the enkephalins Naoto Minamino 1 , Hisayuki Matsuo 2 1Department of Anesthesiology, Miyazaki Medical College 2Department of Biochemistry, Miyazaki Medical College pp.916-933
Published Date 1982/10/10
DOI https://doi.org/10.11477/mf.1431905440
  • Abstract
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 Since the discovery of Met- and Leu-enkephalin as the first endogenous ligands for opiate receptor in 1975, more than 20 endogenous opioid peptides have been identified in brain and other tissues. Recently, chemical information of endogenous opioid peptides and their precursors have been accumulated and they have been proposed to be candidates for a neurotransmitter or a neuromodulator. Physiological functions of these peptides, however, remain to be solved.

 At the present stage, endogenous opioid peptides are classified into three groups, as follows;


Copyright © 1982, Igaku-Shoin Ltd. All rights reserved.

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電子版ISSN 1882-1243 印刷版ISSN 0001-8724 医学書院

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