A survey concerning the effects of kainic acid on the central nervous system Yasuhiko Ibata 1 , Hiroko Lucia Obata 1 , Yoshinori Murabe 1 , Kiminao Mizukawa 2 , Haruo Kinoshita 1 1Department of Anatomy, Kyoto Prefectural University of Medicine 2Department of Pediatrics, Kyoto Prefectural University of Medicine pp.962-971
Published Date 1980/10/10
DOI https://doi.org/10.11477/mf.1431905215
  • Abstract
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 Recently kainic acid (KA) has been used as a tool for scrutinizing the neuron types in the central nervous system since it has been generally accepted to act as neurotoxic agent on the neurons with glutamate receptor. In this present article we mainly described the observation of two subjects revealed in our laboratory; the one was the influence of KA (i.p. injected) on the arcuate nucleus of the rat, the other was the effect of small doses of KA into lateral ventricle upon the hippocampal formation of the rat.

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