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Japanese

Duchenne muscular dystrophy and related diseases: Study on the single skinned fiber Akio TAKAGI 1 1Division of Neuromuscular Research, National Center for Nervous, Mental and Muscular Disorders pp.756-764
Published Date 1980/8/10
DOI https://doi.org/10.11477/mf.1431905193
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Abstract

Single skinned muscle fibers were prepared in chicken and human muscular dystrophy. Isolated single fibers were examined under the phase microscope. When sarcomere length of the fiber was markedly uneven or the fiber was splitted, it was discarded. Thus, on fibers which appeared normal under the light microscopy, function of the contractile system and the sarcoplasmic retic-ulum (SR) was compared between controls and dystrophy.

In chicken dystrophy, maximal tension (P0), which was elicited by 3×10-5M Ca ion, was within the same range as that of normal control.


Copyright © 1980, Igaku-Shoin Ltd. All rights reserved.

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電子版ISSN 1882-1243 印刷版ISSN 0001-8724 医学書院

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