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A Case of Foix-Alajouanine's Disease Masaaki Matsushita 1 , Hiromasa Onda 1 , Kenichi Harada 2 , Taigo Sakaguchi 3 1Department of Pathology, Faculty of Medicine, Tokyo University 2Department of Psychiatry, Faculty of Medicine, Tokyo University 3Department of Internal Medicine, Tokyo Hitachi Hospital pp.721-728
Published Date 1966/12/25
DOI https://doi.org/10.11477/mf.1431904367
  • Abstract
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 In a patient, 49 year-old, male, paresthesia of the gluteal region and weakness of the left foot were firstly noted. Subsequently he developed gradual paraplegia with moderate muscular atrophy, transversal sensory disturbances (L1) and bladder disturbance. Finally sepsis appeared. The total duration of illness was 4 years and 10 months.

 The postmortem examination revealed haeman. gioma racemosum venosum of the spinal ves. sels and necrosis of the spinal cord. Extramedullary haemangioma, from the superior thoracic segment to the sacrar, was associated with marked dilatation and great thickening of the wall, where inflammatory infiltration was not found. Small intramedullary vessels, from the middle thoracic to the asacrar, increased and showed convolution or glomerulus-formation and thickening and hyalinisation of the walls. Medullary changes, in parallel with the changes of the intramedullary vessels, showed rarefaction with demyelinisation and plasmatic infiltrations necrosis, but nerve cells were almost intact. These changes were identical with Foix-Alajouanine's disease.

 The pathogenesis of these disease is discussed. The necrosis of the parenchyma of the spinal cord appeared to be secondary to the vascular lesion, i.e. haemangioma racemosum venosum with degenerated walls.


Copyright © 1966, Igaku-Shoin Ltd. All rights reserved.

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電子版ISSN 1882-1243 印刷版ISSN 0001-8724 医学書院

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