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Japanese

A Case of Bilateral Temporal Softening Naohiko Takahata 1 , Nobuhiro Nishi 1 , Reiji Iizuka 1 , Masaaki Ishido 2 pp.98-102
Published Date 1965/3/25
DOI https://doi.org/10.11477/mf.1431904157
  • Abstract
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This is a 10-year-old boy. The initial symptom was character change such as hyperactivity, lying and swindling. One year after the onset of the illness, he had an epileptic convulsion and then became confused and showed oral tendency and stereotypy. The consciousness became more and more distrubed in 2 months and died of an attackof fever.

The postmortem examination revealed the softe-ning in the bilateral temporal lobes. Microscopica-lly the followings were detected: The spongy state in the subcortical white matter in the temporal lo-bes. The disintegration of nerve cells, especially in the temporal-and occipital lobes. The appeara-nce of Alzheimer type Ⅱ glial cells with intranuc-lear PAS positive inclusion's body, widely dissemi-nated in gray and white matter. The appearance of great number of microglial cells in both white and gray matter.

These histopathological findings of the brain are highly similar to the "Pseudoulegyria Type (Shira-ki)"of hepatocerebral disease. But the clinical course of behavior disorder distinguishes this case from other hepatocerebral disease with episodic bursts of conscious disturbance.


Copyright © 1965, Igaku-Shoin Ltd. All rights reserved.

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電子版ISSN 1882-1243 印刷版ISSN 0001-8724 医学書院

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