インシュローマによる365日間の遷延性低血糖性昏睡の1剖検例

An Autopsy Case of 365 Days' Prolonged Hypoglycemic Coma by Insuloma

I．はじめに

　低血糖性脳障害の脳病理組織学的所見については，インシュリンショック療法による死亡例の報告を多く見出すが，インシュローマによるものの報告例はきわめて少なく，とくに本例は365日間という内外の文献例によつてみても最も長期間にわたる遷延性昏睡後の死亡例であり，その脳病理組織学的所見については，他の低血糖性脳障害および無〜低酸素性脳障害の文献例と対比しつつ考察を加えた。

A 42 years old woman had suffered from uncon-sciousness in the early morning nine times during 17 months. The last coma occured in her house, and was followed by severe convulsions. On the fourth day of the last coma, she was admitted to the hospital, and blood sugar was less than 40 mg/ dl. She was never awakened even by intravenous injection of glucose and steroid, and severe clonic convulsions of her upper, lower limbs and tic of her face were often occurred.