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Neurotransmitters in taste buds Takatoshi NAGAI 1 1Department of Physiology, Teikyo University School of Medicine Keyword: 味細胞 , 神経伝達物質 , セロトニン , メルケル様基底細胞 pp.630-638
Published Date 1999/10/10
DOI https://doi.org/10.11477/mf.1431901080
  • Abstract
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Chemical stimuli are transduced to electrical signal in the taste cell of the taste bud. The electrical signal is transformed through a synapse to neural activities in the gustatory afferents. Neurotransmitters mediating synaptic transfer between taste cells and the afferent nerve fiber are unknown. To date, acetylcholine, norepinephrine, serotonin and neuropeptides have been postulated as candidates. In the amphibian taste bud Merkel-like basal cells contain serotonin and selectively accumulate serotonin applied to incubating medium.Accumulated serotonin is released in aCa2+ dependent manner to change input resistance orCa2+ currents in the taste cell membrane. Thus, serotonin is likely to modulate the function of taste cells.


Copyright © 1999, Igaku-Shoin Ltd. All rights reserved.

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電子版ISSN 1882-1243 印刷版ISSN 0001-8724 医学書院

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