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Neurotrophic factors with great potentialities on motoneuronal degeneration Hiroshi FUNAKOSHI 1 , Toshikazu NAKAMURA 1 1Division of Biochemistry, Department of Oncology, Biomedical Research Center, Osaka University Medical School Keyword: 運動ニューロン , Motor neuron , 神経栄養因子 , neurotrophic factor , ニューロトロフィン , neurotrophin , グリア細胞由来神経栄養因子 , glial cell line-derived neurotrophic factor , GDNF , 肝細胞増殖因子 , hepatocyte growth factor , HGF , 人工神経栄養因子 , synthetic neurotrophic factor pp.885-898
Published Date 1997/12/10
DOI https://doi.org/10.11477/mf.1431901008
  • Abstract
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Neurotrophic factors have been shown to have an important role in the control of generation, survival, dif-ferentiation, and regeneration of neurons in the peripheral and central nervous systems.

Here we have focused on and discussed the possible role of novel neurotrophic activities of neurotrophic factors, which have been recently discovered, in motoneurons. These factors include neurotrophins, glial cell line-derived neurotrophic factor (GDNF) and its relatives : nerturine (NTN), cardiotrophin-1 (CT-1), cystein-rich neurotrophic factor (CRNF), hepatocyte growth factor (HGF) and its family members.


Copyright © 1997, Igaku-Shoin Ltd. All rights reserved.

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電子版ISSN 1882-1243 印刷版ISSN 0001-8724 医学書院

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