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Mechanisms of muscle pain. Kenji KAWAKITA 1 1Department of Physiology, Meiji University of Oriental Medicine Keyword: 筋痛 , 侵害受容器 , 感作 , 関連痛 pp.475-482
Published Date 1998/6/10
DOI https://doi.org/10.11477/mf.1431900861
  • Abstract
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Various mechanisms induce muscle pain. Pain provoked by ischemic muscle contractions is due to algesic substances such as bradykinin or adenosine produced by local acidosis and/or ATP deficiency. Sustained muscle contraction or overload of the muscle induces muscle membrane disruptions and produces inflammatory chemical mediator such as prostaglandin E2 which sensitizes the muscle nociceptors and may activate silent nociceptors.


Copyright © 1998, Igaku-Shoin Ltd. All rights reserved.

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電子版ISSN 1882-1243 印刷版ISSN 0001-8724 医学書院

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