抗不安薬

Anxiolytics: Appropriate Use of Benzodiazepine Receptor Agonists

抗不安薬には，主にベンゾジアゼピン受容体作動薬とセロトニン_1A受容体部分作動薬がある。ベンゾジアゼピン受容体作動薬は，抗不安作用，鎮静催眠作用，筋弛緩作用，抗けいれん作用を有する。奇異反応，離脱症状，依存性が問題となるため，漫然と使用しないことが望ましい。セロトニン_1A受容体部分作動薬は，発現に時間がかかるなどの問題点がある。抗不安薬の種類，それぞれの特性を理解して臨床に臨むことが重要である。

Abstract

Anxiolytics are a class of drugs that include benzodiazepine receptor agonists and serotonin 1A receptor partial agonists. Although benzodiazepine receptor agonists have anxiolytic, sedative-hypnotic, muscle relaxant, and anticonvulsant effects, their use should be carefully monitored due to their potential for paradoxical reactions, withdrawal symptoms, and dependence. On the other hand, serotonin 1A receptor partial agonists have a slower onset, and their use also presents challenges. In clinical practice, having a thorough understanding of the various types of anxiolytics and their unique features is crucial.