炎症性ニューロパチー治療薬

Therapeutic Strategies for Inflammatory Neuropathy

炎症性ニューロパチーの多くは免疫療法で治療可能な疾患である。軸索変性による不可逆的な障害が生じる前に強力な治療を行うことが重要である。免疫療法が治療の中心だが，疾患ごとに薬剤の有効性に差があり，患者ごとに治療反応性が異なることをしばしば経験する。適切な時期に治療効果判定を行うことで，重症例を見極め，患者ごとに最適の治療を選択する必要がある。

Abstract

Most cases of inflammatory neuropathy can be treated. It is important to treat patients before axonal degeneration can cause irreversible damage. Conventional treatments include corticosteroids, intravenous immunoglobulin (IVIg), and plasma exchange. Recently, the efficacy of various immunosuppressive and biological agents has increased. Drug efficacy varies depending on the disease and the underlying pathomechanisms. In addition, patients often respond differently to each treatment; therefore, selecting the most appropriate treatment for each patient by assessing the severity of the disease and the efficacy of drugs at appropriate time points is necessary.