パーキンソン病と関連疾患

Diagnosis of MSA-P and PSP-P in Early Stage

パーキンソン病と，パーキンソン型多系統萎縮症（MSA-P）やパーキンソン型進行性核上性麻痺（PSP-P）との鑑別は，初期には極めて困難で，しばしば誤診される。臨床症候と画像診断を併せて検討することで，MSA-PやPSP-Pを早期に診断できる可能性がある。MSA-Pでは，拡散強調画像やT2^＊強調画像，プロトン密度強調画像の撮像が役に立つ。PSP-Pでは，MRPIが有用である。

Abstract

Differentiating Parkinson's disease (PD) from multiple system atrophy with predominant parkinsonism (MSA-P) or progressive supranuclear palsy-parkinsonism (PSP-P) in early stages of the disease is extremely difficult. MSA-P and PSP-P are often misdiagnosed as PD. MSA-P and PSP-P may be diagnosed in their early stages by considering clinical symptoms and neuroradiological findings together. Diffusion weighted images, T2^＊ weighted images and proton density weighted images are useful for diagnosis MSA-P in early stages , while the magnetic resonance parkinsonism index is useful tool for diagnosis of PSP-P in the early stage.