Japanese

Pathology of Vasculitic Neuropathies Nobuyuki Oka 1 1Department of Neurology, National Hospital Organization Minami-Kyoto Hospital Keyword: 血管炎 , 血管炎性ニューロパチー , 神経生検 , ANCA関連血管炎 , リウマトイド血管炎 , vasculitis , vasculitic neuropathy , nerve biopsy , ANCA-associated vasculitis , rheumatoid vasculitis pp.223-231
Published Date 2016/3/1
DOI https://doi.org/10.11477/mf.1416200381
  • Abstract
  • Look Inside
  • Reference

Abstract

Prompt diagnosis of vasculitis is necessary because neuropathy may be the first symptom of vasculitic syndrome, and it is crucial for the management of patients. Antineutrophil cytoplasmic antibody (ANCA)-associated vasculitis, rheumatoid vasculitis, cryoglobulinemia, Sjogren's syndrome, and non-systemic vasculitic neuropathy are disorders frequently associated with vasculitic neuropathy. Pathological features such as the size of the involved vessels and the type of inflammatory cells, combined with general symptoms and laboratory data, may contribute to the specific diagnosis. ANCA may be involved in the pathogenesis of microscopic polyangiitis, and eosinophilic toxins may injure the nerve fibers in some patients with eosinophilic granulomatosis with polyangiitis. We detected B-cell follicle-like structures adjacent to the inflamed vessels in rheumatoid vasculitis, which may be associated with the pathogenesis.


Copyright © 2016, Igaku-Shoin Ltd. All rights reserved.

基本情報

電子版ISSN 1344-8129 印刷版ISSN 1881-6096 医学書院

関連文献

もっと見る

文献を共有