The Center of Sadness, Pain, and Recognition Richi Niida 1 , Masaru Mimura 1 1Department of Neuropsychiatry, Keio University School of Medicine Keyword: 後部帯状回 , 前部帯状回 , アルツハイマー病 , うつ病 , デフォルトモードネットワーク , posterior cingulate cortex , anterior cingulate cortex , Alzheimer disease , depression , default mode network pp.417-426
Published Date 2017/4/1
DOI https://doi.org/10.11477/mf.1416200759
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The posterior cingulate cortex (Brodmann area, BA 23) is the hub of the default mode network (DMN). Moreover, its network connectivity decreases early in Alzheimer disease. The anterior cingulate cortex (BA 24) is connected to networks such as the DMN, working memory network (WMN), and salience network (SN) and plays a role in network coordination. The subgenual anterior cingulate cortex (sgACC) on the rostral region of the anterior cingulated cortex is suggested to be associated with depression.

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